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After you click on the drug selection box, you may select a drug model by either:
After the model is selected, you may change the length of infusion and edit any of the model parameters:
Target peak and trough.
Dosing weight and Vd per kg, used to calculate Volume of distribution:
Volume of distribution = DW x Vd L/kg
Nonrenal and Renal constants, used to calculate either Kel or CL (depending on the model selected):
Kel (or CL) = Nonrenal + [Renal x CrCl]
Click the calculate button to display the Kel, Vd, and the Ideal dosage regimen for the patient and model selected.
Enter a practical dose and interval. The program then displays an estimated steady-state peak and trough level.
After a dose and interval are entered, the Print and View Graph functions are enabled. Please Note: If you wish to have a serum level graph printed on your dosing consult, click View Graph then click the Save graph button.
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