Field
|
Description
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
Drug name
|
Name of model
(must be a unique name)
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
Vd peripheral
|
Vd peripheral compartment
(L/kg of dosing weight
|
X
|
X
|
X
|
X
|
|
X
|
X
|
Age correction for elderly
|
Vd correction for elderly patients
(age > 65 years)
|
X
|
X
|
X
|
X
|
|
|
|
Wt correction for obesity
|
Use to calculate dosing weight:
DW = LBW + [CF x (ABW-LBW)]
|
X
|
X
|
X
|
X
|
|
|
X
|
Target PK
|
Target peak level, if applicable
|
X
|
X
|
X
|
X
|
|
|
|
Peak time
|
Time in minutes, after the end of the infusion, when the target peak is to be targeted.
|
X
|
X
|
X
|
X
|
|
|
|
Target TR
|
Target trough level
|
X
|
X
|
X
|
X
|
|
X
|
X
|
Infusion
|
Default time of infusion (minutes)
|
X
|
X
|
X
|
X
|
|
X
|
X
|
Vd central
|
Vd central compartment (L/kg)
|
|
|
X
|
X
|
|
|
|
Kel calc or
CL calc
|
Select what is calculated by the equation:
Nonrenal + (CrCl x Renal)
Elimination rate (Kel) or
Clearance (CL)
|
X
|
X
|
|
|
|
|
|
Renal
|
Renal portion of CL/Kel equation:
CL/Kel = Nonrenal + (CrCl x Renal)
|
X
|
X
|
X
|
X
|
|
X
|
X
|
Nonrenal
|
Nonrenal portion of CL/Kel equation:
CL/Kel = Nonrenal + (CrCl x Renal)
|
X
|
X
|
X
|
X
|
|
X
|
X
|
K12
|
Distribution constant central to periph
|
|
|
X
|
X
|
|
|
|
K21
|
Distribution constant periph to central
|
|
|
X
|
X
|
|
|
|
Max dose
|
Max recommended daily dose
(mg/kg/day)
|
X
|
X
|
X
|
X
|
|
X
|
X
|
EI dose
|
Mg/kg dose for extended interval dosing of aminoglycosides
|
X
|
|
|
|
|
|
|
MIC
|
Default minimum inhibitory concentration
|
X
|
X
|
X
|
X
|
|
|
|
SD Vd
|
Population Vd, standard deviation
(needed for Bayesian analysis)
|
X
|
|
X
|
|
|
|
|
SD Kel/Cl
|
Population Kel/Cl, standard deviation
(needed for Bayesian analysis)
|
X
|
|
X
|
|
|
|
|
SD CP1
|
Serum level standard deviation*
(needed for Bayesian analysis)
|
X
|
|
X
|
|
|
|
|
SD CP2
|
Serum level standard deviation*
(needed for Bayesian analysis)
|
X
|
|
X
|
|
|
|
|
SD CP3
|
Serum level standard deviation*
(needed for Bayesian analysis)
|
X
|
|
X
|
|
|
|
|
SD CP fixed
|
Serum level standard deviation*
(needed for Bayesian analysis)
|
X
|
|
X
|
|
|
|
|
Dosing table
|
Dosing table
|
|
X
|
|
X
|
X
|
|
|
Care plan
|
Pharmaceutical care plan
|
X
|
|
X
|
|
|
X
|
X
|