Chloride requirements

Physiology:

Chloride is the most abundant extracellular anion; however its intracellular concentration is small.  It balances out positive charges in the extracellular fluid and by passively following sodium, helps to maintain osmolality.  It plays a role in the ability of blood to carry CO2 to the lungs and is important in potassium conservation.

Empiric daily requirement

Adults:  As needed to balance acid/base (80 to 100 mEq/day)

Infants/children:  As needed to balance acid/base (2 to 4 mEq/kg/day)