WBC and total lymphocytes

Normal: Above 1800

Physiology:

The total lymphocyte count reflects the number of circulating lymphocytes, most of which are T cells. Tissues generating T cells are very sensitive to malnutrition and undergo involution with a decrease in lymphocyte production.  TLC is estimated from WBC and differential: (% lymphocytes X total WBC) / 100.

Low TLC: Less than 800

Causes:

Assessment:

Low  total lymphocyte count is not associated with specific symptoms or signs.

Labs:

Mild deficit:        1200 to 2000

Moderate deficit        800 to 1200

Severe deficit:        Less than 800

TPN correction:

Optimal re-feeding leads to a gradual increase in total lymphocyte count.